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Molecular interactions underlying dorsoventral asymmetry in flowers
Reference
G15131
Principal Investigator / Supervisor
Professor Enrico Coen
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
Cell and Develop Biology
Funding type
Research
Value (£)
188,040
Status
Completed
Type
Research Grant
Start date
01/02/2002
End date
31/01/2005
Duration
36 months
Abstract
The aim is to understand how four key regulatory genes isolated from Antirrhinum, cyc, dich, rad, and div, interact to partition the flower meristem into distinctive regions along the dorsoventral axis. A combination of DNA-binding studies, yeast one and two hybrid assays and RNA in situ hybridisations will be used to determine whether rad is a direct target of CYC and whether RAD antagonises DIV by competitive binding. The role of protein trafficking within and between cell layers will be determined by immunolocalisation. The extent to which these mechanisms are conserved in Arabidopsis, a species with radially symmetrical flowers, will be explored through a combination of gene function and expression studies on cyc and rad orthologues.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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