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Markov Chain Monte Carlo comparative statistical methods to account for phylogetic uncertainty

ReferenceG14980
Principal Investigator / Supervisor Professor Mark Pagel
Co-Investigators /
Co-Supervisors
Institution University of Reading
DepartmentAnimal and Microbial Sciences
Funding typeResearch
Value (£) 153,032
StatusCompleted
TypeResearch Grant
Start date 01/10/2001
End date 31/10/2005
Duration49 months

Abstract

The aim of this research is to develop Markov Chain Monte Carlo (MCMC) comparative methods for the across-species analysis of gene-sequence and other discrete trait evolution on phylogenetic trees. Phylogenies are treated as known without error in comparative studies, even though trees are rarely known with certainty. MCMC methods provide a formal approach to solve the problem of phylogenetic uncertainty. This research will investigate three approaches to combining comparative statistical methods into the MCMC theoretical framework. We shall conduct computer simulation studies of the methods, apply them to real gene-sequence data sets, and develop user-friendly software to be made freely available to researchers.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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