Award details

An investigation into whether mitochondria recombine in humans and other animals

Reference	G14037
Principal Investigator / Supervisor	Professor Adam Eyre-Walker
Co-Investigators / Co-Supervisors	Dr Philip Awadalla, Dr John Maynard Smith
Institution	University of Sussex
Department	Biology and Environmental Science
Funding type	Research
Value (£)	118,776
Status	Completed
Type	Research Grant
Start date	01/05/2001
End date	01/09/2004
Duration	40 months

Abstract

Until very recently it was thought that mitochondria were inherited solely through the maternal line in higher animals, and that their inheritance was therefore clonal. This assumption had been used extensively in the study of human and mitochondrial evolution. The object of this proposal is to investigate in depth whether mitochondria recombine in human and other animals, by extending and increasing the power of two tests of recombination, and by employing several other methods which have recently been published. It is anticipated that our research will both resolve whether recombination occurs in mitochondria, and lead to more powerful tests of recombination which will be useful in diverse fields of genetics.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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