Award details

Cryptochrome and the Drosophila clock

Reference	G13962
Principal Investigator / Supervisor	Professor Ezio Rosato
Co-Investigators / Co-Supervisors	Professor Charalambos Kyriacou
Institution	University of Leicester
Department	Biology
Funding type	Research
Value (£)	166,168
Status	Completed
Type	Research Grant
Start date	01/02/2001
End date	31/07/2004
Duration	42 months

Abstract

Several circadian clock genes have been described in a number of organisms. Amongst these are cryptochromes, blue light photoreceptors found in plants and animals. In plants cryptochromes have photoreceptor activity and are implicated in the clock mechanism. In animals, the situation is more complex. In mammals there are two CRY molecules and both have lost their role as photoreceptors and acquired a function in the central clock. In Drosophila the single copy gene cry has been described as a circadian photoreceptor only. We have evidence that CRY may play a more significant role in the fly's circadian clock, and propose to investigate the role of Drosophila CRY using a variety of in vivo and in vitro methods.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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