BBSRC Portfolio Analyser
Award details
Mutations affecting Ac transpositional activity in Arabidopsis
Reference
G13510
Principal Investigator / Supervisor
Professor Paul Jarvis
Co-Investigators /
Co-Supervisors
Institution
University of Leicester
Department
Biology
Funding type
Research
Value (£)
143,968
Status
Completed
Type
Research Grant
Start date
21/08/2000
End date
21/08/2003
Duration
36 months
Abstract
The research will elucidate the role played by host-encoded factors in controlling the activity of the Ac-type transposons. The iae mutants of Arabidopsis display dramatic increases (approximately 550 fold in the case of iae1-1) in Ac activity (Plant J., 1997, 11: 907-919; Plant J., 1997, 11: 921- 931). The primary aim of the research will be to identify and characterise the IAE1 locus. The iae1 mutation maps to a genomic region which has been entirely sequenced, and so positional cloning will be greatly facilitated. The iae2 mutation will be mapped with a view to cloning the IAE2 locus in the future. Unpublished data suggest that the activities of other transposons related to Ac (Tag1 from Arabidopsis and Tam3 from Antirrhinum) are also elevated in iae1-1. Genetic and transgenic experiments to assess the effect of iae1 on these and other Ac-type elements will be conducted.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search