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Molecular interaction during root hair differentiation between the Arabidopsis genes TIP1 and SHAVEN2
Reference
G13413
Principal Investigator / Supervisor
Professor Claire Grierson
Co-Investigators /
Co-Supervisors
Dr Alison Cavell
Institution
University of Bristol
Department
Biological Sciences
Funding type
Research
Value (£)
170,872
Status
Completed
Type
Research Grant
Start date
01/11/2000
End date
31/12/2004
Duration
50 months
Abstract
The TIP1 gene of Arabidopsis plays an important role in cell elongation, especially during root hair differentiation and pollen tube growth. We are close to identifying the sequence of TIP1, and have genetic evidence that TIP1 is negatively regulated during root hair growth by the locus SHV2 (BBSRC Grant 7/G06940). Our USA-based collaborator has agreed to make the sequence of SHV2 available to us. We propose to probe the mechanism by which TIP1 and SHV2 interact by: 1) analysing and comparing the sequence of TIP1 and SHV2 wild type and mutant alleles; 2) overexpressing the TIP1 and SHV2 proteins in the wild type Arabidopsis; 3) analysing the expression and subcellular localisation of the TIP1 and SHV2 gene products in wild type and mutant root hair cells; and 4) characterising the phenotypes of double mutants with new allele combinations of TIP1 and SHV2.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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