Award details

Molecular population genetics of X- and Y-chromosomal genes in the dioecious plant Silene latifolia

Reference	G13017
Principal Investigator / Supervisor	Professor Deborah Charlesworth
Co-Investigators / Co-Supervisors
Institution	University of Edinburgh
Department	Inst of Cell, Animal and Population Biol
Funding type	Research
Value (£)	133,819
Status	Completed
Type	Research Grant
Start date	01/12/1999
End date	01/12/2002
Duration	36 months

Abstract

I propose new work on the evolution of sex chromosomes in the plant Silene latifolia. The goal to find further X-linked loci, by an approach that has already produced one such locus. Sequence data available for genes in this species will be used to obtain genetic variants, known from my previous work to be abundant in outbreeding plants. The variants will be used to test for sex linkage. I also propose sequence studies of X- and Y- linked loci that have already been discovered by other labs using different approaches, in order to discover whether these are in the pairing or differential segment of the Y. The loci identified will be used to test for degeneration of Y-linked homologues, define different Y- chromosomal regions, to study sequence diversity, for quantitative expression studies to test for dosage compensation, and for linkage studies to illuminate the origin of sex chromosomes.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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