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The evolutionary change of codon preferences in the virilis group of Drosophila

ReferenceG12707
Principal Investigator / Supervisor Professor Brian Charlesworth
Co-Investigators /
Co-Supervisors
Institution University of Edinburgh
DepartmentInst of Cell, Animal and Population Biol
Funding typeResearch
Value (£) 166,772
StatusCompleted
TypeResearch Grant
Start date 01/07/2000
End date 01/07/2003
Duration36 months

Abstract

The genomic DNA sequences of a set of at least 30 genes will be determined, in three species of the virilis group of Drosophila, plus an outgroup, D. hydei. This will enable determination of the direction and rate of change in codon preferences among both closely and distantly related species. Studies of within-species variation in DNA sequences for a sub-set of these genes will be conducted, in order to assess the strength and direction of selection on synonymous codons. The sequence data that will be generated by this project are relevant to other important evolutionary questions about genome organisation and evolution.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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