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Novel approaches towards determining the effect of histone acetylation on chromatin structure
Reference
G12115
Principal Investigator / Supervisor
Professor Tom Owen-Hughes
Co-Investigators /
Co-Supervisors
Institution
University of Dundee
Department
College of Life Sciences
Funding type
Research
Value (£)
164,128
Status
Completed
Type
Research Grant
Start date
01/09/2000
End date
01/09/2003
Duration
36 months
Abstract
There is a history of evidence linking histone acetylation to gene regulation. More recently, the identification of a number of the enzymes responsible for the acetylation of histones has demonstrated the importance of this process in the regulation of many genes. Despite the general role acetylation lays in gene regulation, the pathway by which it affects transcription is not clear. This proposal involves the use of powerful new approaches to study the effect of acetylation on chromatin structure. These will be combined with the aim of furthering our understanding of how histone acetylation affects gene regulation.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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