Award details

Significance of a non-coding endogenous antisense frequency transcript for circadian clock function in Neurospora crassa

ReferenceG12106
Principal Investigator / Supervisor Dr Susan Crosthwaite
Co-Investigators /
Co-Supervisors
Institution The University of Manchester
DepartmentLife Sciences
Funding typeResearch
Value (£) 160,912
StatusCompleted
TypeResearch Grant
Start date 01/12/1999
End date 01/12/2002
Duration36 months

Abstract

The significance and mechanism of action of an antisense transcript potentially involved in the generation of a circadian oscillator in Neurospora crassa will be investigated. Proof of a function will be determined from the molecular and overt phenotype of strains in which the antisense transcript is abolished. Biochemical and molecular studies will investigate which processes are regulated and how this regulation is achieved. This work will result in a better understanding of the components required to build a circadian oscillator and will significantly increase what is known about the role of endogenous antisense transcripts in eukaryotes.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
terms and conditions of use (opens in new window)
export PDF file