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Testing a theory of genomic imprinting: resource competition and its effects on embryonic and placental growth
Reference
G11786
Principal Investigator / Supervisor
Professor Laurence Hurst
Co-Investigators /
Co-Supervisors
Professor Andrew Ward
Institution
University of Bath
Department
Biology and Biochemistry
Funding type
Research
Value (£)
163,168
Status
Completed
Type
Research Grant
Start date
01/04/2000
End date
01/04/2003
Duration
36 months
Abstract
Our aim is to test the following three predictions of the conflict theory of genomic imprinting: 1) That placental growth and embryonic growth are related by a v shaped function. 2) That proliferation of some placental cell types is associated with embryonic growth. 3) That between-brood competition for resources can exist. We shall make use of the growth retarding properties of the Igf2 knockout mouse to manipulate the level of resource competition.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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