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The control and evolution of morphology by the Hox gene Ultrabithorax
Reference
G11778
Principal Investigator / Supervisor
Professor David Stern
Co-Investigators /
Co-Supervisors
Institution
University of Cambridge
Department
Zoology
Funding type
Research
Value (£)
52,579
Status
Completed
Type
Research Grant
Start date
01/04/2000
End date
31/03/2001
Duration
12 months
Abstract
The statement - genetic variation generates morphological variation, though true, is useless. We lack an empirical understanding of the process, and hence remain ignorant of potential molecular rules for generating variation. I propose to study how molecular variation in Ultrabithorax (Ubx) generates morphological variation. I previously demonstrated that Ubx has evolved to contribute to variation in leg trichome patterns between drosophilids. The proposed work aims to identify the relevant regulatory regions and determine if their evolution has caused this morphological variation. Further, I aim to identify other trichome patterning genes and determine whether these too have evolved to generate morphological variation.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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