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The role of gap junction-mediated intercellular communication in Drosophila

Reference	G11639
Principal Investigator / Supervisor	Dr Jane Davies
Co-Investigators / Co-Supervisors	Professor Jonathan Bacon, Professor David Sattelle
Institution	University of Sussex
Department	Biology and Environmental Science
Funding type	Research
Value (£)	498,696
Status	Completed
Type	Research Grant
Start date	01/10/1999
End date	01/06/2003
Duration	44 months

Abstract

Although the exchange of small molecules through gap junctions during development is well documented, the specific role that this plays during development is not clear. The identification of at least some components of gap junction channels in Drosophila (the innexins) enables the sophisticated molecular biology of the fly to be used for functional studies. Our task is now to characterise the functional properties of innexin proteins and further elucidate their roles in development, the regulation of cell proliferation, and the functioning of gap junctions in mature systems (electrical synapses).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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