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Identification and physical and genetic characterisation of plasmid stability determinants from Gram-positive bacteria
Reference
G11604
Principal Investigator / Supervisor
Dr Finbarr Hayes
Co-Investigators /
Co-Supervisors
Institution
The University of Manchester
Department
Life Sciences
Funding type
Research
Value (£)
141,623
Status
Completed
Type
Research Grant
Start date
06/09/1999
End date
06/09/2002
Duration
36 months
Abstract
Active partition, multimer resolution, and toxin-antitoxin systems promote the stable distribution of low-copy number plasmids of Gram-negative bacteria. However, remarkably little is known about the mechanisms which contribute to the segregational stability of low copy number plasmids of Gram-positive bacteria. Segregational stability determinants will be isolated from selected plasmids of Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus, Listeria monocytogenes, and Lactococcus sp.) and will be characterised genetically and physically.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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