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Cloning and characterisation of TLM1 a putative component of the Arabidopsis circadian clock
Reference
G10362
Principal Investigator / Supervisor
Professor Isabelle Carre
Co-Investigators /
Co-Supervisors
Institution
University of Warwick
Department
Biological Sciences
Funding type
Research
Value (£)
170,574
Status
Completed
Type
Research Grant
Start date
26/10/1998
End date
26/10/2001
Duration
36 months
Abstract
Work in my laboratory has identified one putative component of the circadian clock in Arabidopsis. We have shown that the LHY gene encodes a transcription factor of the MYB family, which verifies several of the properties expected of oscillator components. In addition, we have recently identified another gene (TLM1) which, when mutated, abolished nyctinastic leaf movements and impaired the plant's perception of photoperiod. These results suggested that TLM1, like LHY, may encode an essential component of the circadian clock. This project aims to 1) further characterise the phenotypes of the tlml mutant, 2) clone the gene, 3) determine its site of action in the circadian regulatory network, and 4) test its genetic and physical interactions with LHY and other genes that regulate circadian rhythmicity and photoperiodic responses.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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