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Cell-autonomy of the ELF3 and LHY functions in circadian timing
Reference
G10325
Principal Investigator / Supervisor
Professor Andrew Millar
Co-Investigators /
Co-Supervisors
Institution
University of Warwick
Department
Biological Sciences
Funding type
Research
Value (£)
127,624
Status
Completed
Type
Research Grant
Start date
18/01/1999
End date
18/01/2001
Duration
24 months
Abstract
The circadian clock is an intracellular regulator that controls circadian rhythms, and is present in many, if not all cells. The observed rhythms of intact organisms indicate that the clocks of different cells are co-ordinated. We have privileged access to two of the three genes that are known to abolish circadian rhythms in Arabidopsis: LHY may be clock component, whereas elf3 affects the interaction of light signals with the rhythm. We will characterise a novel allele of elf3 to determine the mechanism of this arrhythmia. Our luciferase bioimaging methods allow us to test the cell-autonomy of circadian rhythms in plants for the first time, using novel genetic mosaics to determine whether LHY and ELF3 affect cell-to-cell co-ordination.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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