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A screen for novel Drosophila mutants in a simple automated learning paradigm.
Reference
G09666
Principal Investigator / Supervisor
Professor Cahir O'Kane
Co-Investigators /
Co-Supervisors
Institution
University of Cambridge
Department
Genetics
Funding type
Research
Value (£)
280,269
Status
Completed
Type
Research Grant
Start date
09/07/1998
End date
09/07/2001
Duration
36 months
Abstract
The fruitfly Drosophila is a useful model organism in behavioural research. A number of learning and memory paradigms have been defined in Drosophila, including habituation of a jump reflex. We wish to identify novel learning mutations in Drosophila, by screening for mutants that are defective in this habituation. Insertional mutagenesis will be used, to give a convenient approach to cloning and characterisation of the genes affected. This approach offers a way to identify and characterise important molecular components of the process, without any preconceptions about their biochemical function, and such components are also likely to be involved in similar cellular processes in other organisms.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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