BBSRC Portfolio Analyser
Award details
QTL analysis in Arabidopsis using overlapping chromosome substitution lines
Reference
G09258
Principal Investigator / Supervisor
Professor Michael Kearsey
Co-Investigators /
Co-Supervisors
Professor Henry John Newbury
,
Dr Harpal Pooni
Institution
University of Birmingham
Department
Sch of Biosciences
Funding type
Research
Value (£)
333,292
Status
Completed
Type
Research Grant
Start date
01/09/1998
End date
01/09/2001
Duration
36 months
Abstract
Current population based methods of QTL location are too coarse for accurate gene targeting. We aim to map QTL controlling developmental and morphological traits in Arabidopsis more accurately using lines derived from the Landsberg-Columbia resource population. These lines will involve overlapping substitutions generated by marker assisted backcrossing allowing mapping to approx. 10cM. Subsequent crossing between lines together with additional markers in the critical regions will improve accuracy to approx.1cM even for QTL of low heritability and will provide information on their genetic effects. Such accuracy will provide a basis for map based gene cloning. The lines produced will form an important resource for gene mapping in the future.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search