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Circadian regulators of light-activated CAB transcription identified by the luciferase reporter gene
Reference
G08667
Principal Investigator / Supervisor
Professor Andrew Millar
Co-Investigators /
Co-Supervisors
Institution
University of Warwick
Department
Biological Sciences
Funding type
Research
Value (£)
199,495
Status
Completed
Type
Research Grant
Start date
03/11/1997
End date
03/11/2000
Duration
36 months
Abstract
The CAB genes of higher plants are activated by light and rhythmically regulated by the circadian clock. The clock interacts with light signalling, to dramatically modulate (or gate) CAB activation in response to light. CAB transcription is induced strongly during the day, but very weakly at night. The bioluminescent cab2::luc reporter reveals this circadian gating in intact, transgenic Arabidopsis. We will use photoreceptor mutants to determine which of the known photoreceptor pathways is gated by the clock. We will identify gating mutants, in order to dissect the molecular mechnisms involved. Two candidate mutants have been identified and further mutants will be recovered in new screens, including transposon-induced alleles.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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