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Characterisation of the AXR3 gene of Arabidopsis and its partial suppresser SAX1

ReferenceG08626
Principal Investigator / Supervisor Professor Ottoline Leyser
Co-Investigators /
Co-Supervisors
Institution University of York
DepartmentBiology
Funding typeResearch
Value (£) 159,331
StatusCompleted
TypeResearch Grant
Start date 01/01/1998
End date 31/01/2001
Duration37 months

Abstract

Mutant analysis indicates that the AXR3 gene of Arabidopsis is important in regulating responses to the plant hormone auxin. We have mapped the AXR3 gene to a 34kb region on chromosome 1 and should soon have its sequence. This project aims to continue the molecular analysis of AXR3 and to identify its biochemical function. We will use a combination of reverse and forward genetic approaches to achieve this. In particular, we have isolated a extragenic mutation (sax1-1) which can partially suppress the axr3-1 phenotype. This mutation may define a gene involved in modulating AXR3-mediated responses and this hypothesis will be tested.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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