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Functional analysis of plant MADS-box genes
Reference
G07952
Principal Investigator / Supervisor
Professor Brendan Davies
Co-Investigators /
Co-Supervisors
Institution
University of Leeds
Department
Plant Biochemistry & Biotechnology
Funding type
Research
Value (£)
146,882
Status
Completed
Type
Research Grant
Start date
01/11/1997
End date
01/11/2000
Duration
36 months
Abstract
We aim to begin the systematic isolation and functional analysis of all members of an important plant transcription factor gene family - MADS-box genes. Plant MADS-box genes encode many structurally related proteins which control development. The work forms two overlapping parts: isolation and function search. Gene isolation will be by homology methods (mixed probe low stringency screening, PCR), computer searches (other species, ESTs) and non-homology based screens for MADS protein interactions. Function search will be by PCR selection of loss-of-function mutants from large populations. Genetic interactions will be determined by crossing the obtained mutants with each other and with existing mutants.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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