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Molecular studies on Ftsk a highly conserved cell division and putative DNA mobilising protein
Reference
G06722
Principal Investigator / Supervisor
Dr Susan Dewar
Co-Investigators /
Co-Supervisors
Institution
Heriot-Watt University
Department
Sch of Life Sciences
Funding type
Research
Value (£)
176,198
Status
Completed
Type
Research Grant
Start date
17/03/1997
End date
30/09/2000
Duration
43 months
Abstract
This proposal seeks to characterise the function of the essential E. coli cell cycle protein FtsK in septation and nuclear segregation. A combination of in vivo and in vitro methodologies will be used to establish the nature of FtsK's association with the membrane and its interaction with the proteins involved specifically in septation. The functional domains of the protein will be defined by the use of targeted mutagenesis, by the genetic analysis of newly isolated mutant alleles of FtsK and from examining the biochemical properties of the purified protein. We will also study the genetic organisation of the ftsK locus and its association with the lrp regulon.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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