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Molecular architecture of Escherichia coli FNR protein

Reference	G06544
Principal Investigator / Supervisor	Professor Steve Busby
Co-Investigators / Co-Supervisors	Professor J Green, Professor J Guest
Institution	University of Birmingham
Department	Sch of Geography, Earth & Env Sciences
Funding type	Research
Value (£)	171,282
Status	Completed
Type	Research Grant
Start date	01/04/1997
End date	01/04/2000
Duration	36 months

Abstract

FNR protein is a transcriptional factor essential for E. coli to adapt to anaerobic growth conditions. FNR activates transcription at some promoters and represses transcription at others. Our objective is to identify the surface-exposed patches of FNR that are essential for gene activation and repression and to investigate how they interact with RNA polymerase to modulate transcription. Additionally, we propose to locate surface-exposed regions of FNR that interact with two other factors, NarL and NarP.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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