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Molecular biology of cell division and differentiation in Bacillus subtilis
Reference
G04953
Principal Investigator / Supervisor
Professor Jeffery Errington
Co-Investigators /
Co-Supervisors
Institution
University of Oxford
Department
Sir William Dunn Sch of Pathology
Funding type
Research
Value (£)
709,218
Status
Completed
Type
Research Grant
Start date
01/10/1995
End date
01/10/1999
Duration
48 months
Abstract
We wish to study the molecular biology of cell division and differentiation in the gram-positive bacterium Bacillus subtilis. We shall attempt to isolate and characterise genes required for cell division, septum positioning and chromosome partitioning, by genetical and sequence comparison methods. We will investigate the functions and regulation of these genes by a range of cytological and molecular biological approaches. We will apply similar methods to determine how key transcription factors that operate during sporulation respond to changes in cell morphology, including formation of the division septum. Also, how some of the proteins controlled by these transcription factors contribute to spore morphogenesis.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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