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Molecular cytogenetics of meiosis in cruciferae; DNA-DNA in situ hybridisation to synaptonemal complexes
Reference
G04051
Principal Investigator / Supervisor
Dr G Jones
Co-Investigators /
Co-Supervisors
Dr David Marshall
Institution
University of Birmingham
Department
Sch of Biosciences
Funding type
Research
Value (£)
148,598
Status
Completed
Type
Research Grant
Start date
01/09/1995
End date
01/06/1998
Duration
33 months
Abstract
The main thrust of this proposal is to exploit in situ hybridisation of DNA probes to synaptonemal complex (SC) preparations from plant meiocytes (Brassica oleracea; Arabidopsis thaliana). The extended nature of meiotic SCs, combined with in situ hybridisation will be used to produce high resolution physical (cytological) maps of genes and DNA sequences. Genome and chromatin organisation during meiotic prophase will also be investigated by in situ hybridisation with the aim of furthering our understanding of the SC- chromatin interaction and its relationship to key meiotic processes such as synapsis and homologous recombination.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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