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Molecular dissection of and mechanism of action of a translational enhancer present within a cell-specific transcript in plants
Reference
G03154
Principal Investigator / Supervisor
Professor David Twell
Co-Investigators /
Co-Supervisors
Professor Gary Foster
Institution
University of Leicester
Department
Medicine - Pathology
Funding type
Research
Value (£)
137,944
Status
Completed
Type
Research Grant
Start date
22/11/1993
End date
22/04/1997
Duration
41 months
Abstract
1) To define sequences within the lat52 5' untranslated leader which mediate translational enhancement and to determine whether enhancement operates by a mechanism involving internal ribosome entry. 2) To determine the developmental regulation of the translational initiation factor eIF-4A and the potential involvement of a pollen-specific eIF-4A gene from tobacco in regulating translation of the lat52 transcript. 3) To investigate whether cellular proteins present in germinating pollen are capable of specific binding to the lat52 5' untranslated leader, and to isolate and characterise cDNAs encoding such proteins.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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