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Genetic engineered eukaryotic cell lines: their use to generate proproteins and related endoproteolytic products

ReferenceG02774
Principal Investigator / Supervisor Dr Maria Castro
Co-Investigators /
Co-Supervisors
Institution The University of Manchester
DepartmentLife Sciences
Funding typeResearch
Value (£) 127,583
StatusCompleted
TypeResearch Grant
Start date 14/03/1995
End date 14/03/1998
Duration36 months

Abstract

1. To use the expression vector pEE12 to establish stably transfected AtT20 and GH3 cell lines expressing pre-procorticotrophin-releasing hormone (pre-proCRH). 2. To establish stably transfected CHO-K1 cell lines co-expressing PC2 or PC3 and pre-proCRH cDNAs. 3. To investigate the endoproteolytic cleavages affecting proCRH synthesised within the systems used.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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