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Functional analysis of eukaryotic transcriptional complexes using surface plasmon resonance
Reference
G02000
Principal Investigator / Supervisor
Professor Peter Stockley
Co-Investigators /
Co-Supervisors
Professor Philip Gilmartin
Institution
University of Leeds
Department
Inst of Integrative & Comparative Biolog
Funding type
Research
Value (£)
121,055
Status
Completed
Type
Research Grant
Start date
01/04/1995
End date
31/12/1998
Duration
45 months
Abstract
We will use the technique of surface plasmon resonance (SPR) to probe interactions between a number of plant transcription factors and their DNA targets. In vitro transcription would be established on the SPR sensor chip. Isolated factors from binding assays will be characterised in full, allowing the molecular mechanisms of their physiological roles to be investigated. The interaction of the transcriptional apparatus with chromatin structure will be investigated.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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