Award details

Isolation and characterisation of yeast kinetochores

ReferenceG01998
Principal Investigator / Supervisor Dr E Mellor
Co-Investigators /
Co-Supervisors
Institution University of Oxford
DepartmentBiochemistry
Funding typeResearch
Value (£) 129,329
StatusCompleted
TypeResearch Grant
Start date 01/12/1994
End date 01/12/1997
Duration36 months

Abstract

1) To characterise the protein components of the yeast kinetochore, isolated in the form of chromatin from nuclei, using a combination of 1d and 2d gel electrophoresis, radioactive labels, cross-linking reagents and western blotting with antibodies. 2) To examine changes to the protein composition of the kinetochore during the cell cycle in synchronised cells or cells arrested by temperature sensitive mutation and in cells under going meiosis.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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