Award details

Sequence organisation and expression in a selfish chromosome

Reference	G01643
Principal Investigator / Supervisor	Professor Glyn Jenkins
Co-Investigators / Co-Supervisors	Dr J Forster, Professor Robert Jones
Institution	Aberystwyth University
Department	Inst of Rural Studies
Funding type	Research
Value (£)	133,514
Status	Completed
Type	Research Grant
Start date	05/12/1994
End date	05/06/1997
Duration	30 months

Abstract

The clones of a microlibrary derived from microdissected B- chromosomes will be characterised with respect to copy number, B- specificity, sequence homology and chromosomal location. Parts of the B-chromosome will be microdissected in order to enrich for clones containing desirable sequences. Gene expression and modulation of transcriptional activity of B-chromosomes will be explored by differential screening of cDNA libraries. A detailed and thorough understanding of the molecular organisation and genetic activity of the B is seen as a preliminary to its evaluation and development as a plant artificial chromosome for the transformation of rye and related species.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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