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Negative regulation of Erwinia virulence determinants: analysis of the new RepE global repression regulon

ReferenceG01587
Principal Investigator / Supervisor Professor George Salmond
Co-Investigators /
Co-Supervisors
Institution University of Warwick
DepartmentUniversity of Warwick Department
Funding typeResearch
Value (£) 134,050
StatusCompleted
TypeResearch Grant
Start date 09/05/1994
End date 09/05/1997
Duration36 months

Abstract

In this study we will investigate a novel global repression regulon (the RepE regulon) of Erwinia carotovora. This regulon includes the virulence factors of this potato pathogen. We will study the binding of RepE to its target sites (REB sites) and sequence novel genes downstream of the REB sites to identify the proteins of the global repression regulon. We will sequence the repE gene and identify the RepE protein in expression systems. We will analyse regulation of the repE gene using gene fusions.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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