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The role of specific growth factors, particularly a new vascular endothelial growth factor (VEGF) and its expression, localisation and function in the establishment of pregnancy
Reference
FG11419
Principal Investigator / Supervisor
Professor Steve Charnock-Jones
Co-Investigators /
Co-Supervisors
Institution
University of Cambridge
Department
Department of Obstetrics & Gynaecology
Funding type
Research
Value (£)
8,644
Status
Completed
Type
Fellowships
Start date
01/04/1998
End date
01/04/1999
Duration
12 months
Abstract
The objectives of the project are to determine: i) sites of expression of VEGF and its receptors flt and flk in the uterus of the mouse and pig during pregnancy; ii) whether an alteration of VEGF production is involved in failure of pregnancy in mice stocks with high resorption rates; iii) how and by what, is VEGF synthesis regulated in the uterus; iv) the responses of placental cells bearing VEGF receptors to stimulation with recombinant VEGF; and v) what is the outcome of pregnancy if the action of VEGF is nullified by passive immunisation.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Fellowship - Fellowship Grant (FG) [1997-2001]
Funding Scheme
X – not Funded via a specific Funding Scheme
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