Award details

Structural and functional changes of muscle-tendon in ageing: implications for locomotion

Reference	ERA16254
Principal Investigator / Supervisor	Professor Marco Narici
Co-Investigators / Co-Supervisors	Professor Constantinos Maganaris, Professor Alberto Minetti
Institution	Manchester Metropolitan University
Department	Exercise and Sports Science
Funding type	Research
Value (£)	226,612
Status	Completed
Type	Research Grant
Start date	15/05/2002
End date	14/09/2005
Duration	40 months

Abstract

The study aims at investigating the effect of ageing on the structure and function of the muscle-tendon complex, and the relevance of these changes to locomotory performance. Measurements will be taken on young healthy adults and elderly healthy individuals. In vivo measurements of muscle structure and force-length characteristics, and tendon mechanical properties, will be taken on the gastrocnemius and vastus lateralis muscle-tendon units using ultrasound and Magnetic Resonance Imaging. Kinetic and kinematic measurements will be taken during walking and during ascending and descending stairs, with additional mechanical and metabolic energy measurements during walking. To examine the effect of ageing, differences in muscle-tendon structure/function between groups will be quantified and correlated with the measurements taken during the locomotor tasks examined.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Experimental Research on Ageing (ERA) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

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