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Ageing in the parasitic nematode Strongyloides ratti

Reference	ERA16140
Principal Investigator / Supervisor	Professor Mark Viney
Co-Investigators / Co-Supervisors	Professor David Gems
Institution	University of Bristol
Department	Biological Sciences
Funding type	Research
Value (£)	176,644
Status	Completed
Type	Research Grant
Start date	01/04/2002
End date	01/10/2004
Duration	30 months

Abstract

Many animals alter their rate of ageing in response to environmental cues. In the nematode Strongyloides ratti, life span varies approximately 50-fold between genetically identical parasitic and free-living adult female morphs. We propose to perform the first detailed description of ageing in this remarkable species. Ageing will be characterised and compared in these morphs in terms of biodemography, and behavioural, structural and biochemical markers of ageing. We will establish whether a phenomenologically similar process of ageing occurs at different rates in the long-lived parasitic and short-lived free-living adult forms of S. ratti. We will also use comparisons of long- and short-lived S. ratti adults to test the free-radical theory of ageing.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Experimental Research on Ageing (ERA) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

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