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The structure and function of the gastrointestinal mucus barrier: physiology, pharmacology and nutritional aspects
Reference
EII05483
Principal Investigator / Supervisor
Professor A Allen
Co-Investigators /
Co-Supervisors
Professor Jeff Pearson
Institution
Newcastle University
Department
School of Cell and Molecular Biosciences
Funding type
Research
Value (£)
15,000
Status
Completed
Type
Research Grant
Start date
01/02/1996
End date
01/02/1999
Duration
36 months
Abstract
To understand the properties and functions of the adherent gastrointestinal mucus barrier, it is necessary to isolate and purify the component mucins. The established method for isolating pure mucins is by equilibrium centrifugation in a CsCl density gradient. This application is for a preparative ultracentrifuge to underpin mucin preparation on a number of projects on gastrointestinal mucins in conjunction with Reckitt & Colman Worldwide Pharmaceuticals and under the BBSRC Equipment and Industry Initiative.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Equipment and Industry Initiative (EII) [1995]
Funding Scheme
X – not Funded via a specific Funding Scheme
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