Award details

Agonist specific coupling of insect octopamine receptors

ReferenceEII05476
Principal Investigator / Supervisor Dr Peter Evans
Co-Investigators /
Co-Supervisors
Institution Babraham Institute
DepartmentBabraham Institute Department
Funding typeResearch
Value (£) 9,048
StatusCompleted
TypeResearch Grant
Start date 26/02/1996
End date 26/02/1998
Duration24 months

Abstract

The project will investigate the phenomenon of agonist-specific coupling of receptors to different second messenger systems using cloned insect octopamine receptors. Locust octopamine receptor subtypes will be cloned using a combination of homology and expression cloning. Their abilities to couple to second messenger systems will be examined by expression in Xenopus oocytes and clonal cell lines. Particular attention will be focused on the possibility that these receptors may be directly coupled to ion channels in an agonist-specific manner.

Summary

unavailable
Committee Closed Committee - Animal Sciences (AS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Equipment and Industry Initiative (EII) [1995]
Funding SchemeX – not Funded via a specific Funding Scheme
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