Award details

Genome manipulation with novel site-specific recombinases

Reference	EGH16108
Principal Investigator / Supervisor	Dr William Brown
Co-Investigators / Co-Supervisors	Professor John Brookfield, Professor Rupert Fray, Professor Margaret Smith, Professor Panos Soultanas
Institution	University of Nottingham
Department	Sch of Biology
Funding type	Research
Value (£)	980,512
Status	Completed
Type	Research Grant
Start date	01/02/2002
End date	30/11/2006
Duration	58 months

Abstract

Precise, targeted manipulation of genome structure is fundamental to the analysis of biological problems at the molecular level. In many organisms this can only be achieved via the use of site-specific recombination systems. This consortium aims to combine its skills in microbiology, protein chemistry, cell biology and plant molecular biology to establish a novel group of recombinases as prime reagents for genome manipulation. The enzymes will be exploited in novel ways to analyse problems of human disease and vertebrate cell biology and develop methods of engineering safer genetically manipulated plants.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Exploiting Genomics: Healthcare, Pharmaceuticals (EGH) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

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