Award details

Exploiting the genome of an insect pathogenic bacterium: Photorhabdus

Reference	EGA16183
Principal Investigator / Supervisor	Professor Stuart Reynolds
Co-Investigators / Co-Supervisors	Dr David Clarke, Dr Nicholas Waterfield
Institution	University of Bath
Department	Biology and Biochemistry
Funding type	Research
Value (£)	1,170,788
Status	Completed
Type	Research Grant
Start date	01/01/2002
End date	31/12/2006
Duration	60 months

Abstract

Photorhabdus is a potent source of new insecticides and drugs. This bacterium is pathogenic to its insect host and any invading organisms (non-host nematodes, bacteria and fungi) but symbiotic with its own nematode host. We propose to develop a postgenomic framework for the exploitation of the Photorhabdus genome using genomic, transcriptome and proteomic approaches. This program will focus on a comparative analysis of three strains each with different biological activities. We will employ state of the art techniques to identify and characterise both virulence factors (potential insecticides and nematicides) and also factors involved in symbiosis (interaction with the nematode host).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Exploiting Genomics: Agri, Food and Environment (EGA) [2001]
Funding Scheme	X – not Funded via a specific Funding Scheme

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