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Regulation of metabolic networks at the level of gene expression - a systems approach to metabolic engineering
Reference
E20443
Principal Investigator / Supervisor
Professor Lee Sweetlove
Co-Investigators /
Co-Supervisors
Dr Nicholas Kruger
,
Professor Richard Ratcliffe
Institution
University of Oxford
Department
Plant Sciences
Funding type
Research
Value (£)
190,289
Status
Completed
Type
Research Grant
Start date
01/12/2003
End date
30/11/2006
Duration
36 months
Abstract
Increased productivity is a pre-requisite for the sustained economic viability of the agriculture industry and the targeted manipulation of plant metabolism is one means by which to achieve this. Metabolic engineering requires a complete understanding of the relationship between changes in specific gene-products (principally enzymes) and fluxes through the metabolic networks of the plant cell. This proposal seeks to provide experimental data from the model plant, Arabidopsis thaliana, that will allow the relationship between changes in the complement of expressed genes and key metabolic fluxes to be investigated. This information will allow the identification of potential genetic targets for the engineering of plant metabolism.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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