Award details

Analytical biomimetic recognition scaffolds as ligands with in-built amplification for SPR arrays

Reference	E19751
Principal Investigator / Supervisor	Professor Elizabeth Hall
Co-Investigators / Co-Supervisors
Institution	University of Cambridge
Department	Institute of Biotechnology
Funding type	Research
Value (£)	188,832
Status	Completed
Type	Research Grant
Start date	01/03/2004
End date	31/10/2007
Duration	44 months

Abstract

This application is concerned with biomimetic molecular scaffolds as constructs for new analytical reagents. Interactive evolutionary computing methods have been used to design analytical reagents, compatible with amplified SPR, that may be expanded in a modular combinatorial fashion for creation of analytical arrays. The programme involves the synthesis of biomimetic recognition ligands linked to a novel SPR amplifier and their assembly and testing on SPR devices. Data from the ligands will be used to further optimise and evolve the design model, achieving compatibility between molecular recognition/transduction and instrument to produce some prototype designs for SPR sensor array systems. (Joint with E19752).

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

E19752 Analytical biomimetic recognition scaffolds as ligands with in-built amplification for SPR arrays

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