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Making artificial receptors accessible - molecular imprinting at surfaces and interfaces
Reference
E19366
Principal Investigator / Supervisor
Professor Andrew Mayes
Co-Investigators /
Co-Supervisors
Institution
University of East Anglia
Department
Chemistry
Funding type
Research
Value (£)
183,844
Status
Completed
Type
Research Grant
Start date
24/07/2003
End date
23/07/2005
Duration
24 months
Abstract
Non-covalent molecular imprinting systems are proposed whereby the receptor sites formed are placed deliberately at the accessible surface of the imprinted polymer materials, where they will be capable of rapid binding and release of template molecules and template-tagged macromolecules. Two techniques will be developed: (i) Imprinting of macro-templates - templates molecules immobilised on the surface of silver nanoparticles. Imprinting of these will generate cavities with clusters of receptors at their surface; (ii) Using the interface of a surfactant vesicle to insert surfactant-derivatised template molecules into the imprinting phase during nanoparticle synthesis. This will produce surface imprinted core-shell nanoparticles.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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