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An individual-based mathematical model of chick embryo gastrulation: developing a virtual embryo computational tool

Reference	E18787
Principal Investigator / Supervisor	Professor Mark Chaplain
Co-Investigators / Co-Supervisors	Dr Bakhtier Vasiev, Professor Kees Weijer
Institution	University of Dundee
Department	Mathematics
Funding type	Research
Value (£)	134,940
Status	Completed
Type	Research Grant
Start date	01/09/2003
End date	31/08/2006
Duration	36 months

Abstract

The primary aim of the research is to develop a mathematical model that will be used to analyse the mechanisms controlling the rearrangement of cells during the fundamental developmental process of gastrulation in the chick embryo experimental system. The key feature of this model is that it will consider the mechano- chemical properties of individual cells responding to signalling cues from cytokines and the surrounding tissues, based on experimental data. The secondary aim of the research is to develop a more general computational tool (based on individual cell properties) that will be made public at the end of the project. Other important modelling applications of the tool include cancer growth, tissue engineering and wound healing.

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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