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Interaction of the cationic polymer chitosan with plasmid DNA and artificial membranes
Reference
E18262
Principal Investigator / Supervisor
Professor Margaret Lawrence
Co-Investigators /
Co-Supervisors
Dr David Barlow
,
Professor Trevor Forsyth
Institution
King's College London
Department
Pharmacy
Funding type
Research
Value (£)
27,100
Status
Completed
Type
Research Grant
Start date
01/10/2002
End date
31/03/2005
Duration
30 months
Abstract
Neutron scattering studies (neutron reflectivity and small angle neutron scattering) will be performed exploiting the technique of contrast variation to study the interaction of the cationic polymer, chitosan, used to produce gene vectors, with DNA and artificial membranes mimicking those of cell membranes. The detailed structural information resulting from these studies will be used to aid in the rationale design of improved gene vectors.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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