Award details

Construction of biofilm consortia with defined internal architecture

Reference	E15770
Principal Investigator / Supervisor	Professor Gerardus Hendricus Markx
Co-Investigators / Co-Supervisors	Professor Gillian Stephens
Institution	The University of Manchester
Department	Chem Eng and Analytical Science
Funding type	Research
Value (£)	189,228
Status	Completed
Type	Research Grant
Start date	02/01/2002
End date	01/04/2005
Duration	39 months

Abstract

Biofilm consortia with defined internal architecture will be constructed by sequentially attracting different microbial species to specified locations in a micro- electrode array, and subsequently immobilising the cells. Using molecular techniques (insertion of GFP genes and using microbe specific rRNA probes) the location of individual species and their activities will be monitored. The performance of the constructed consortia in terms of biochemical process rates of model substrates (chlorobiphenyls, benzylalcohol, nitriles) will be determined using GC/LC/MS. The aim is to exploit spatial organisation in consortia to give more efficient metabolism and enhanced protection against toxic stress.

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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