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Engineering plants for the phytodetoxification of explosives

ReferenceE15011
Principal Investigator / Supervisor Professor Neil Bruce
Co-Investigators /
Co-Supervisors
Professor James Murray
Institution University of Cambridge
DepartmentInstitute of Biotechnology
Funding typeResearch
Value (£) 259,082
StatusCompleted
TypeResearch Grant
Start date 01/04/2001
End date 30/04/2003
Duration25 months

Abstract

Plants offer many advantages over bacteria as agents for bioremediation; however, they typically lack the degradative capabilities of specially selected bacteria. Transgenic plants expressing microbial degradative genes could combine the best advantages of both systems. To investigate this possibility in the context of bioremediation of explosive residues, this project aims to generate transgenic plants expressing PETN reductase, aromatic nitroreductase and RDX lyase; these are enzymes from explosives degrading bacteria. Work will focus on expanding the range of explosives that a single transgenic plant can simultaneously degrade. A particular objective of this project will be the introduction of PETN reductase and nitroreductase into yellow poplar; an environmentally robust plant that has potential for in situ bioremediation. (MOD joint grant scheme).

Summary

unavailable
Committee Closed Committee - Engineering & Biological Systems (EBS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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