Award details

Solid supported Cu(II) fluorosensors for environmental and medical applications

Reference	E12737
Principal Investigator / Supervisor	Professor Marcel Jaspars
Co-Investigators / Co-Supervisors	Professor Jorg Feldmann, Professor Peter Robertson
Institution	University of Aberdeen
Department	Chemistry
Funding type	Research
Value (£)	137,650
Status	Completed
Type	Research Grant
Start date	05/01/2000
End date	01/03/2003
Duration	38 months

Abstract

The main aim is to generate Cu(II) selective fluorescent chemosensors for use in medical and environmental applications. The Cu(II) binding site is derived from the marine metabolites, the patellamides, which are Cu(II) selective in the presence Mg(II), Ca(II), Ni(II), Co(II) and Zn (II). We have designed a solid phase synthesis towards modified patellamides containing two fluorescent oxine groups. The intention is to make several of these in a combinatorial fashion, changing sidegroups so that binding properties can be optimised. The sensor will be supported on a solid support for analysis of biological fluids and environmental samples. This will enable accurate fluorescence intensity measurements to be taken..

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search