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A novel strategy for bioanalytical and biocatalytic devices : biomolecule immobilisation on nanoporous TiO2 electrodes
Reference
E11939
Principal Investigator / Supervisor
Professor James Durrant
Co-Investigators /
Co-Supervisors
Professor Anthony Cass
,
Professor Gianfranco Gilardi
Institution
Imperial College London
Department
Chemistry
Funding type
Research
Value (£)
191,904
Status
Completed
Type
Research Grant
Start date
10/04/2000
End date
10/04/2003
Duration
36 months
Abstract
On the basis of a successful pilot study, we have recently patented the use of nanoporous metal oxide films as a substrate for protein immobilisation for biotechnological applications. Our preliminary studies have already demonstrated the feasibility of protein immobilisation on nanoporous Ti02 films without loss of activity, and remarkably efficient protein/Ti02 electrode electron transfer without the addition of any promoters/mediators. In the light of these successes, we propose to conduct a systematic study of the parameters controlling protein immobilisation and protein/nanoporous Ti02 electrochemical activity which will underpin future biotechnological applications of this strategy.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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