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Integrated planar silicon technologies for high density screening of antibiotics

Reference	E11649
Principal Investigator / Supervisor	Professor Adrian Walmsley
Co-Investigators / Co-Supervisors	Professor S Aitchison, Professor Jonathan Cooper
Institution	University of Glasgow
Department	Infection & Immunity
Funding type	Research
Value (£)	272,431
Status	Completed
Type	Research Grant
Start date	01/05/1999
End date	31/07/2002
Duration	39 months

Abstract

We propose to develop an optical biochip technology for the detection of inhibitors of antibiotic pumps, with application for screening for novel antibiotics. This will involve the development of a high-density microanalytical array for performing optical assays, based upon either fluorescence or bioluminescence. The devices will provide a range of new, but generic technologies, for the rapid, high throughput, detection of target ligands from chemical libraries. The technology will have general applicability in screening for compounds of pharmacological interest.

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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