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Isothermal titration calorimetric analysis of the formation of complexes between immunoglobulins and mutated immunoglobulin-binding domains from protein L of Peptostreptococcus magnus
Reference
E10136
Principal Investigator / Supervisor
Professor Michael Gore
Co-Investigators /
Co-Supervisors
Institution
University of Southampton
Department
Centre for Biological Sciences
Funding type
Research
Value (£)
82,182
Status
Completed
Type
Research Grant
Start date
02/11/1998
End date
01/11/2001
Duration
36 months
Abstract
To analyse the binding interactions between a single domain of protein L from Peptostreptococcus magnus and immunoglobulins by isothermic calorimetry. Detailed thermodynamics data will be used for the identification and generation of mutant species with favourable binding characteristics for the detection and isolation of immunoglobulins.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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