Award details

Development and optimisation of an immunological and cellular tool-kit for pollutant biosensing

Reference	E09606
Principal Investigator / Supervisor	Professor Graeme Paton
Co-Investigators / Co-Supervisors	Professor Andrew Porter
Institution	University of Aberdeen
Department	Plant and Soil Science
Funding type	Research
Value (£)	139,456
Status	Completed
Type	Research Grant
Start date	12/06/1998
End date	12/06/2001
Duration	36 months

Abstract

A toolkit using a combination of antibody fragment and lux-based biosensor technologies will probe for pollutants. The first phases will require the independent optimisation of these techniques for target analytes. The innovative aspect of this project will be the harmonisation of an immunological and cellular approach enabling the predictive assessment of both the bioavailable compartment and the total concentration of specific pollutants. There will be a focus on data interpretation and comparative biosensor performance to enable confident predictions. The selected targets will be model herbicides and phthalate esters. Phthalate esters, which have been labelled as pseudo-oestrogenic compounds (and are priority pollutants in the US) have physiochemical traits that pose problems in assessing bioavailability. It is anticipated that these technologies will in the future be tailored to be toxin and site specific.

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search